There is a release of norepinephrine from the descending inhibitory bulbospinal neurons that binds to alpha-2-receptors in the dorsal horn to reduce afferent ache transmission and generate analgesia. As a result, medicines like clonidine that focus on alpha-2 receptors can affect the transmission of soreness. Jun ten, 2024 · https://barryd492pja6.fliplife-wiki.com/user