Connect with your health care provider if you take any of those drugs and get swollen reduced limbs. Find out more about popular medication Uncomfortable side effects. "Periorbital edema" is a time period for swelling within the eyes. At times men and women seek advice from this issue as "periorbital puffiness" https://www.sgvascularctr.com/swollen-leg-why-do-i-have-it-and-what-can-i-do/