Abstract Pancreatic cancer is one of the most lethal solid malignancies. with few treatment options. We have recently shown that expression of protease activated receptor (PAR)-1 in the tumor microenvironment drives the progression and induces the chemoresistance of pancreatic cancer. As thrombin is the prototypical PAR-1 agonist. https://www.markbroyard.com/hot-save-turbo-air-m3f24-1-n-29-wide-m3-series-reach-in-freezer-featuring-one-solid-door-energy-star-on-sale-top-super/