About 80% of TTP is triggered by deficient activity of ADAMTS13. ADAMTS13 deficiency could be constitutive, because of biallelic ADAMTS13 pathogenic variants; or obtained, as a result of an inhibitory antibody. Evaluation of ADAMTS13 action is done applying tests according to the capability in the protease to cleave common VWF https://water-cooled-chillers62603.sharebyblog.com/34238398/the-smart-trick-of-air-handling-units-ahus-that-no-one-is-discussing