Pentobarbital will lessen the extent or impact of lumacaftor/ivacaftor by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. pentobarbital will decrease the extent or influence of lumefantrine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Coadministration with powerful CYP3A4 inducers can result in diminished serum concentrations and... https://heinzq012wma1.bleepblogs.com/profile