Sensitivity to bicuculline is described by IUPHAR as A serious criterion from the definition of GABAA receptors  GABAergic neurotransmission is altered in hyperammonemic rats, which present increased GABAergic tone from the cerebellum. Long-term therapy with bicuculline, a GABAA receptor antagonist, restores GABAergic tone, the purpose of the glutamate-nitric oxide-cGMP pathway https://chancefevrm.blogthisbiz.com/34957357/what-does-adenosine-5-diphosphate-mean